JAMA Network -AUGUST 11, 2018

Weekly Highlights

  AUGUST 11, 2018

These featured articles published during the past week have been selected by our editors. Click below to read them on the JAMA Network website for free.

RESEARCH

Effect of a Behavioral Intervention for Underserved Preschool-Age Children on Change in BMI
JAMA
This randomized clinical trial compares the effects of a 36-month multicomponent behavioral intervention for obesity prevention vs a school-readiness control on body mass index (BMI) trajectories in underserved preschool-age children at risk for obesity but not yet obese.
 
Preventing Obesity in Children: A Glimmer of Hope (Editorial)
 

RESEARCH

Long-term Concurrent Use of Stimulants and Opioids Among Adults With ADHD
JAMA Network Open
This cross-sectional analysis of US Medicaid files from 29 states investigates the prevalence of and risk factors associated with concurrent stimulant and opioid use among Medicaid-enrolled adults with attention-deficit/hyperactivity disorder.
 
 
 

RESEARCH

Association of Interleukin 6 Receptor Variant With CVD Effects of IL6R Blocking Therapy
JAMA Cardiology
This phenome-wide association study assesses clinical associations between interleukin 6 receptor (IL6R) single-nucleotide polyporphisms and known IL6R drug effects and whether large biobanks and genetics can be used to assess potential beneficial and adverse effects of therapeutic agents with known pathways and related genes.
 
 
 

RESEARCH

Application of the McDonald Criteria for Multiple Sclerosis to Patients With a Typical Clinically Isolated Syndrome
JAMA Neurology
This study evaluates the diagnostic accuracy of the 2017 McDonald criteria vs the 2010 criteria to predict clinically definite multiple sclerosis in patients with a typical clinically isolated syndrome.
 
 
 

RESEARCH

OCT-Guided Laser Therapy for Patients With Recurrent Respiratory Papillomatosis
JAMA Otolaryngology - Head & Neck Surgery
This in vivo study investigates the ability of optical coherence tomography to provide imaging guidance during laser therapy for patient-tailored treatment of pediatric patients with laryngeal recurrent respiratory papillomatosis.
 
 
 

RESEARCH

Effect of Depth of Sedation in Older Patients Undergoing Hip Fracture Repair on Postoperative Delirium
JAMA Surgery
This randomized clinical trial evaluates the effect of lighter vs higher sedation levels during spinal anesthesia on incident delirium in patients who were undergoing hip fracture repair.
 
Depth of Propofol Sedation and Postoperative Delirium: The Jury Is Still Out (Invited Commentary)
 

RESEARCH

Association of Parent and Offspring Religiosity With Offspring Suicide Ideation and Attempts
JAMA Psychiatry
This 3-generation family study examines the association of parent and offspring religiosity with suicide ideation and attempts among children and adolescents in these families.
 
 
 

RESEARCH

Evaluation of a Brief Dermatologist-Delivered Intervention vs Usual Care on Sun Protection Behavior
JAMA Dermatology
This longitudinal controlled cohort study examines the association of a brief dermatologist-delivered intervention with patient satisfaction and sun protection behavior among adults receiving dermatology care.
 
 
 

CLINICAL REVIEW & EDUCATION 

Technique for Nonsurgical Lifting Procedures Using Polydioxanone Threads
JAMA Facial Plastic Surgery
This Surgical Pearl presents the technique for performing nonsurgical lifting procedures with polydioxanone threads.
 
 
 

RESEARCH

Effect of Anlotinib on Overall Survival of Patients With Advanced Non–Small Cell Lung Cancer
JAMA Oncology
This randomized clinical trial examines the efficacy of anlotinib compared with placebo as a third-line or further therapy on overall survival of adult patients with advanced non–small cell lung cancer.
 
 
 

RESEARCH

Association of Fellow Eye With Study Eye Disease Trajectories in CIGTS Participants
JAMA Ophthalmology
This post hoc analysis of participants in the Collaborative Initial Glaucoma Treatment Study estimates the time between initial glaucoma treatment of the study eye and the need for treatment of the fellow eye and ascertains the concordance between rates of progression.
 
The “Curse” of the Fellow Eye in Glaucoma (Invited Commentary)
 

RESEARCH

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature
JAMA Pediatrics
This case-control study identifies a whole-blood gene expression signature that distinguishes children with Kawasaki disease in the first week of illness from other febrile conditions.
 
 
 

CLINICAL REVIEW & EDUCATION

Lessons From the Canadian Experience With Single-Payer Health Insurance
JAMA Internal Medicine
This Special Communication explores the strengths, challenges, and lessons learned following the introduction of the Canadian single-payer health care system in the late 1960s, comparing this system with health care approaches in other countries, including the United States.
 
Drawing Lessons From Canada’s Experience With Single-Payer Health Insurance (Invited Commentary)

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